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Manual Therapy Benefits Patients with Shoulder Pain. Subacromial impingement syndrome occurs when the rotator cuff tendons become inflamed or irritated as they pass through the subacromial space, which can lead to pain, weakness, and reduced range of motion in the shoulder. In a study involving 26 patients with acute subacromial impingement syndrome, researchers observed that those treated with manual therapy for four weeks experienced significant improvements with respect to pain, function, and range of motion. Doctors of chiropractic often utilize a combination of manual therapy and exercise to treat patients with subacromial impingement syndrome and musculoskeletal conditions of the shoulder. Journal of Back and Musculoskeletal Rehabilitation, September 2019